Turning data into cures

Turning data into cures

Pharmaceutical companies adopt knowledge graphs to drive R&D (videos from PMWC 2020)

Pharmaceutical companies adopt knowledge graphs to drive R&D (videos from PMWC 2020)

We recently joined forces with the Precision Medicine World Conference to organize a session on semantic knowledge graphs in drug discovery and clinical trials. The session focused on how pharmaceutical and biotech companies are implementing new interpretable semantic AI technologies (combining machine learning and knowledge graphs) to continuously update knowledge

Join us at the 2020 Precision Medicine World Conference (PMWC)

Join us at the 2020 Precision Medicine World Conference (PMWC)

Data4Cure is thrilled to be part of this year’s Precision Medicine World Conference (PMWC), the largest annual conference dedicated to precision medicine. PMWC’s mission is to bring together recognized leaders, top global researchers, medical professionals, and innovators across healthcare and biotechnology sectors to showcase practical content in an

In the News: Drug Information Association's Magazine

In the News: Drug Information Association's Magazine

Check out the July 2019 issue of the Drug Information Association (DIA) Digital Forum Magazine [https://globalforum.diaglobal.org/issue/july-2019/?_ga=2.194942825.591083740.1579027794-1299344399.1579027794] for our own article on Using Semantic AI In Biomedicine! DIA’s Magazine offers expert coverage of the discovery, development, regulation, surveillance, and

The 2019 Meeting of the American Association for Cancer Research (AACR)

The 2019 Meeting of the American Association for Cancer Research (AACR)

Data4Cure was excited to be part of the 2019 Annual Meeting of the American Association for Cancer Research (AACR), the world’s oldest and largest professional association that focuses on cancer research. As part of the Session on Late-Breaking Research: Bioinformatics, Convergence Science, and Systems Biology [https://www.abstractsonline.com/

Single cell analysis of immunotherapy resistance pathways in the context of the CURIE Knowledge Graph

Single cell analysis of immunotherapy resistance pathways in the context of the CURIE Knowledge Graph

Greetings! This week in our technology section of the blog we are covering the Data4Cure Single-cell RNA-seq Analysis App – part of the Biomedical Intelligence Cloud App Engine. We will focus on analysis of two recently published single-cell datasets looking at identifying biomarkers for immunotherapy response/resistance:Jerby-Arnon et al., Cell,

Focus on nonalcoholic fatty liver disease and steatohepatitis pathways: data resources and analyses on the platform

Focus on nonalcoholic fatty liver disease and steatohepatitis pathways: data resources and analyses on the platform

A few weeks ago we wrote about the extensive updates to the CURIE Knowledge Graph (reaching 1 billion data-driven and literature-mined relations) [https://blog.data4cure.com/new-year-major-updates-platform/] and a new Data Resources framework [https://blog.data4cure.com/new-year-major-updates-platform/] integrating and semantically indexing thousands of biomedical datasets within the Data4Cure Biomedical

Mapping immunotherapy resistance pathways with biomedically-informed AI [Data4Cure @ PMWC 2019]

Mapping immunotherapy resistance pathways with biomedically-informed AI [Data4Cure @ PMWC 2019]

Despite the groundbreaking success of immune checkpoint inhibitor (ICI) therapies in hard-to-treat cancers, still only a fraction of patients show long-term clinical benefit. With the rapidly accumulating molecular, pathologic and clinical data from clinical trials and cancer cohorts, the question is how to best leverage these data to identify better

Focus on inflammatory bowel disease pathways: data resources and analyses on the platform

Focus on inflammatory bowel disease pathways: data resources and analyses on the platform

A few weeks ago we wrote about the extensive updates to the CURIE Knowledge Graph (reaching 1 billion data-driven and literature-mined relations) [https://blog.data4cure.com/new-year-major-updates-platform/] and a new Data Resources framework [https://blog.data4cure.com/new-year-major-updates-platform/] in DataHub for semantic integration and indexing of thousands of datasets. To

Knowledge graph surpassing 1 billion biomedical relations and a new Data Resources framework

Knowledge graph surpassing 1 billion biomedical relations and a new Data Resources framework

Greetings and Happy New Year! We are happy to report that the Data4Cure Biomedical Intelligence®Cloud and CURIETMKnowledge Graph are once again significantly expanding to help with a yet broader set of tasks in pharmaceutical R&D. With the updates this month, the CURIE Knowledge Graph is reaching1 billion data-driven

Data4Cure @ PMWC 2018: Combining systems biology, machine learning and tumor evolution to improve biomarkers for IO

Data4Cure @ PMWC 2018: Combining systems biology, machine learning and tumor evolution to improve biomarkers for IO

A key challenge in the field of immunotherapy is predicting which patients will respond to IO therapy either as a single agent or in combination with other treatments. Clinical and experimental strategies involve testing expression of individual markers or gene panels, assessing tumor mutation burden and MSI status, and more

PMWC Interview with Data4Cure's Janusz Dutkowski

In a recent interview featured on the PMWC Blog, our CEO and co-founder, Janusz Dutkowski, Ph.D., considers how machine learning and systems biology are transforming biomedical research and discusses the challenges in pharmaceutical R&D addressed by the Data4Cure Platform. Learn more from the PMWC Blog: > PMWC Interview with

Data4Cure's Talk at Big Data in Precision Medicine Conference

Data4Cure's Talk at Big Data in Precision Medicine Conference

Please join us at the Big Data in Precision Medicine Conference in Washington, DC,Oct. 31 – Nov. 1, 2017. We will present new applications on our Biomedical Intelligence Cloud platform and discuss approaches which apply advanced machine learning and AI algorithms to continuously update biomedical knowledge. Janusz Dutkowski, CEO of

Global Precision Medicine & Biomarkers Leaders Summit

Global Precision Medicine & Biomarkers Leaders Summit

We are excited to be part of the 4thGlobal Precision Medicine & Biomarkers Leaders Summit [http://www.global-engage.com/event/precision/]taking place on September 21-22, 2017 in Munich, Germany. Data4Cure will co-host an immunooncology roundtable with Dr. Pallavi Sachdev, Director, Oncology Biomarker Research, Clinical Research, Eisai. Please join us as

Data4Cure featured in GEN

Data4Cure featured in GEN

Genetic Engineering & Biotechnology News (GEN) featured Data4Cure, Inc. in the article Machines Learn to Sift Big Biodata [http://www.genengnews.com/gen-articles/machines-learn-to-sift-big-biodata/6045?q=data4cure] by Kristen Slawinski, Ph.D. GEN is the premier biotech publication since its launch in 1981. Here are some highlights from the article: “As

Data4Cure to present at BioData World West 2017

Data4Cure to present at BioData World West 2017

How can AI and machine learning extend biomedical knowledge and not add to the noise and complexity that hamper progress in the field? Meet us at the BioData West [http://www.terrapinn.com/conference/biodata-west/index.stm] conference in San Francisco, April 26-27. We will present new applications on our

Watch videos from our PMWC 2017 session

precision medicine

Watch videos from our PMWC 2017 session

In January Data4Cure hosted a session [https://blog.data4cure.com/data4cure-chair-session-pmwc-2017/] at the Precision Medicine World Conference (PMWC) in Mountain View, CA focused on molecular subtyping in clinical drug development.The session highlighted some of the unique new aspects of the Biomedical Intelligence® Cloud [https://blog.data4cure.com/biomedical-intelligence-cloud-features-new-tools/] in

Join us at Biomarker and NGS Data Analysis and Informatics Conferences

Join us at Biomarker and NGS Data Analysis and Informatics Conferences

Please join Data4Cure at the annual Biomarker and NGS Data Analysis and Informatics Conferences to be held on February, 6-7 in San Diego, CA. The pursuit of driving precision medicine and the quest to refine a biomarker model for immuno-oncology drug development, the event aims to gather experts from pharma,

Data4Cure's AI-Powered Biomedical Intelligence Cloud Features New Tools for Immuno-Oncology

Data4Cure's AI-Powered Biomedical Intelligence Cloud Features New Tools for Immuno-Oncology

La Jolla, CA,January 24, 2017/PRNewswire/ — Data4Cure, Inc. today announced a series of updates and new case studies using its Biomedical Intelligence® Cloud – a semantic data-driven discovery platform designed to continuously grow knowledge from a multitude of genomic, molecular and clinical data that are accumulating rapidly in the field.

Data4Cure to organize a session at the upcoming PMWC 2017

Janusz Dutkowski, CEO, Data4Cure will be chairing a session on “How Molecular Subtyping Can Aid Clinical Drug Development [http://pmwcintl.com/2017sv/sessionthemes-how-molecular-subtyping-can-aid-clinical-drug-development/?utm_campaign=Data4Cure%20Outreach&utm_content=&utm_source=Data4Cure&utm_medium=LinkedIn&utm_term=2017] ” at the upcoming 2017 Precision Medicine World Conference (PMWC) Silicon Valley. Pallavi

How knowledge is born: putting data in context

How knowledge is born: putting data in context

Data is transforming biology and medicine. In many biomedical domains we have more data every year than collectively ever before – the consequence of exponential growth. Yet data is not knowledge. And growing knowledge has proven a lot more challenging than sheer data accumulation. Finding new drug targets, biomarkers, and personalized

Boosting statistical power and context with Multiscale Maps of the Cell

Boosting statistical power and context with Multiscale Maps of the Cell

The hierarchy It is not about components, it’s about the machine. Like many other complex systems, biological machines are hierarchical: proteins interacting in complexes which work as part of pathways forming more general processes and so on. To better understand disease mechanisms we need to be able to interrogate

Data4Cure at the 2016 Bio-IT World Conference & Expo

Data4Cure at the 2016 Bio-IT World Conference & Expo

Janusz Dutkowski, PhD, CEO and co-founder of Data4Cure will give a talk at the 2016 Bio-IT World Conference & Expo in Boston – a premier event featuring IT and informatics enabling technologies that drive biomedical research, drug discovery & development, and clinical and healthcare initiatives. His talk titledGenomic Variants in Context and at

Join us at the 2016 NGS Data Analysis and Biomarker Conferences

Join us at the 2016 NGS Data Analysis and Biomarker Conferences

Join us at the 2016 NGS Data Analysis Conference and the Biomarker Conference co-organized in our home town and learn more about bioinformatics and NGS. Data4Cure’s CEO, Janusz Dutkowski, PhD will be presenting on Thursday February 18 at 10 am. His talk is titled “Translating data into knowledge, translating

Data4Cure's Biomedical Intelligence Cloud featured in GenomeWeb

Data4Cure's Biomedical Intelligence Cloud featured in GenomeWeb

GenomeWeb features Data4Cure in an article on ITOMIC Pan-Omic Breast Cancer Trial and talks about results from our collaboration with the University of Washington Center for Cancer Innovation. Data4Cure’s Biomedical Intelligence Cloud was used towards intensive longitudinal monitoring and bioinformatics data analysis. Janusz Dutkowski, PhD, CEO of Data4Cure has

Precision medicine in breast cancer: Data4Cure's platform used in research published in JNNC

Precision medicine in breast cancer: Data4Cure's platform used in research published in JNNC

Data4Cure’s Biomedical Intelligence Platform has been used in a research published in theJournal of the National Comprehensive Cancer Network [http://www.jnccn.org/site/misc/terms.xhtml]in February 2016. The article describes theIntensive Trial of OMics in Cancer (ITOMIC), a novel approach to clinical research that brought together